Concern over safety of SAGM blood.
نویسندگان
چکیده
منابع مشابه
Differences in Rat and Human Erythrocytes Following Blood Component Manufacturing: The Effect of Additive Solutions.
BACKGROUND Small animal models have been previously used in transfusion medicine studies to evaluate the safety of blood transfusion products. Although there are multiple studies on the effects of blood banking practices on human red blood cells (RBCs), little is known about the effect of blood component manufacturing on the quality of rat RBCs. METHODS Blood from Sprague-Dawley rats and huma...
متن کاملInfusion of P-Capt prion-filtered red blood cell products demonstrate acceptable in vivo viability and no evidence of neoantigen formation.
BACKGROUND Transmission of variant Creutzfeldt-Jacob disease (vCJD) is a major concern in blood transfusion. The P-Capt filter has been shown to remove around 4 log ID(50) prion infectivity from prion-spiked human red blood cells (RBCs). STUDY DESIGN AND METHODS Two independent, single-center, randomized, open-label studies were designed to analyze the safety of P-Capt-filtered RBCs. RBCs pre...
متن کاملSerial assessment of biochemical parameters of red cell preparations to evaluate safety for neonatal transfusions
BACKGROUND AND OBJECTIVES Neonatologists often prefer fresh blood (<7 days) for neonatal transfusions. The main concerns for stored RBCs are ex vivo storage lesions that undermine red cell functions and may affect metabolic status of neonatal recipients. This study was designed to evaluate serial in vitro changes of biochemical parameters in different RBC preparations during storage to consider...
متن کاملRed cell apheresis with automated in-line filtration.
BACKGROUND The aim of this study was to provide data on concurrent red blood cell (RBC) and platelet (PLT) apheresis with RBC in-line leukoreduction and automated addition of saline-adenine-glucose-mannitol (SAGM) using the new version (V6.0) of Trima Accel®. METHODS In this two-center paired study, each subject completed a test and a control procedure with an interval of 9 weeks between proc...
متن کاملOccult Hepatitis B Infection and Its Role in Blood Safety: a Review
Background: Blood transfusion plays a great role in public health and the blood safety still has remained a main concern. HBV has been considered as one of the most prevalent blood borne infections. It is estimated that chronic HBV affects 350-400 million people worldwide. Comprehensive knowledge about HBV has high importance in Iran due to high number of blood dependent patients. Material ...
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عنوان ژورنال:
- Archives of disease in childhood
دوره 63 1 شماره
صفحات -
تاریخ انتشار 1988